Letrozole (Femara) Powders

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Description

Letrozole is a drug indicated for the treatment of breast cancer in postmenopausal women. It is a drug that belongs to the aromatase class of drugs. Letrozole is indicated for treatment in women with hormone receptor positive early breast cancer. It is prescribed for first-line treatment of postmenopausal women with hormone receptor positive. Letrozole may also be indicated for the treatment of advanced breast cancer in postmenopausal women. Patients are advised to make all necessary laboratory studies in order to depict the hormone receptor breast cancer. It is a drug that does not cause addiction. Letrozole is a hormonal therapy due to the fact that it interferes with the hormones receptor positive breast cancer. It is contraindicated in patients with a known hypersensitivity to it or to any of its ingredients. It is also contraindicated in women with premenopausal endocrine evidence. Prior to commencing the therapy with Letrozole, consult a doctor and get informed about possible side effects, potential interaction with other drugs and other important information related to the use of Letrozole.

Femara Letrozole Properties

Product Name Letrozole
Trade Name Femara
Appearance White Crystal Powder
Sample Picture
Molecular Structure
Biological Half-Life 2 days
CAS Number 112809-51-5
Formula C17H11N5
Molar mass 285.303 g/mol
Certification HSE, ISO 9001, USP
Suitable for Adult
Purity >99%
Functions Female Breast Cancer Treatment
Reship Policy Reship for Fee
State Solid

Femara Letrozole Uses

Letrozole is used treat early breast cancer in women who have experienced menopause and who have had other treatments, such as radiation or surgery to remove the tumor. It is also used to treat early breast cancer in women who have experienced menopause and who have already been treated with a medication called Tamoxifen (Nolvadex) for 5 years.
Letrozole is also used in women who have experienced menopause as a first treatment of breast cancer that has spread within the breast or to other areas of the body or in women whose breast cancer has worsened while they were taking Tamoxifen.

How Femara Letrozole works?

Letrozole lowers the levels of the female sex hormone oestrogen in the body. Oestrogen stimulates some breast cancers to grow. These breast cancers are called hormone sensitive or hormone receptor positive. Letrozole can stop or slow the growth of these cancers. Letrozole only works in women who have had their menopause.
After the menopause, women don’t produce oestrogen from their ovaries. But they still produce a small amount by using an enzyme called aromatase which turns other sex hormone called androgens into oestrogen. This change happens mainly in fatty tissue, muscle and the skin. Letrozole is a type of drug called an aromatase inhibitor. It blocks aromatase so that it can’t change the androgen into oestrogen.

Femara Letrozole COA

Tests

Specifications

Results

Appearance

White or off-white Crystalline Powder

White
Crystalline Powder

Solubility

Soluble in Chloroform;
Soluble in ethanol when heated

Conform

Melting points

182ºC-184ºC

182ºC

Related substances

≤0.5%

0.3%

Single impurity

≤0.3%

0.2%

Loss on drying

≤1.0%

0.8%

[Assay]C17H11N5
(On anhydrous basis)

≥98.0%

99.2%

Conclusion

Conforms Specifications of Enterprise Standard.

Femara Letrozole Liquid Oral Recipes

Highest Concentration Made 5mg/ml, Just For Reference Only
Material Requested:
1 gram of Letrozole powder
19.9 ml’s PEG 300
179.1 ml’s of 190 Proof Grain Alcohol

Manufacturing Steps
1.Prepare a hot water bath. Boil water in microwave or on a pot. Once boiling starts remove from heat.
2.Place PEG and powder in beaker.
3.Place the beaker deep enough in to the water so that the hot water is level with the PEG and powder. Gently swirl or stir with a stir rod until solution is clear. Reheat water as needed.
4.Allow PEG to cool some. Then add in your 190 proof alcohol. You don’t have to do this drop by drop but don’t just dump it in. Pour it in slowly.
5.Stir or gently shake until mixed.

Questions & Answers

1.What’s your delivery time?
We will arrange the delivery within 24 hours after receiving the payment, except for custom products.
2.What kind of payments does you support?
T/T, Western Union, Money Gram, Bank Transfer.
3.What’s the MOQ?
Generally speaking, the MOQ is 10 gram, but we also can provide you samples for quality inspection.
4.Do you charge for the samples?
According to our company policy, we just charge the samples based on EXW price. And we will return the samples fee during the next order.
5.Can you  packing according to customers’ requirements?
Sure, if you have a request for packing, please tell us, any good ideas are welcomed.