YK11 is a selective androgen receptor modulator (SARM), which activates AR without the N/C interaction. In this study, we further investigated the mechanism by which YK11 induces myogenic differentiation of C2C12 cells. The induction of key myogenic regulatory factors (MRFs), such as myogenic differentiation factor (MyoD), myogenic factor 5 (Myf5) and myogenin, was more significant in the presence of YK11 than in the presence of DHT. YK11 treatment of C2C12 cells, but not DHT, induced the expression of follistatin (Fst), and the YK11-mediated myogenic differentiation was reversed by anti-Fst antibody.
Myogenic differentiation is in reference to the products ability to block myostatin. Myostatin inhibition has been a really popular movement since the ban of most prohormones as it looks to be a relatively unexplored area for muscle growth and fat loss. There are currently a lot of claims about mystatin inhibition, but not so much factual data on these products. YK11 will have similar affects to DHT (possibly more potent) without the negatives of DHT. What this means is that the product will most likely be suppressive and require a post cycle, but not cycle support. It also won’t have androgenic side affects like hair loss, acne, etc. The increase in follistatin caused by YK11 will act as an antagonist to mystatin (it will block myostatin) as well as the anabolic growth properties of YK11.
|Synonyms||((17α,20E)-17,20-[(1-methoxyethylidene)bis(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester; YK-11;|
|Molar mass||430.54 g·mol−1|
|Certification||GMP, ISO 9001, USP, BP|
|Policy||Free Reship Policy|
YK11 actually increases the ability to generate muscle so is often used within a bulking cycle but it can also help during cutting too. This is because it will only add lean mass, and not just bulk. Therefore, it can prevent the loss of muscle which can occur when calorific intake is slashed making it ideal for cutting cycles.
Although still in its infancy, the potential uses for YK11 on a bulking cycle are almost limitless. Early indications suggest that this could be the strongest SARMs to hit the market providing the greatest potential for adding sheer muscle. The compound works by inhibiting the action of myostatin on the muscle which in turn allows for far superior muscle growth.
YK11 Dosage Details
So how much should you be taking every day? If you are looking to experience all of these great benefits then you need to make sure that you take 5mg a day. If you have taken SARMS before or if you are experienced with them then you may be able to take 10mg a day so you can benefit even more so this is something you need to keep in mind when you are taking them and planning your doses. Of course, if you do take over this amount then you may experience some side effects and this is something you will want to avoid. If you do take more then you may find that you don’t get as many positive effects either so keep this in mind as well. Let’s move on to what else you need to know about this and what it means for you and your body. YK11 is a steroidal molecule that has shown effects in cellular assays. That means that there have yet to be any results published for animals and humans, but it is already taking the internet by storm in terms of the sales and it is a well known anabolic SARM as well.
Our Hot Sale SARMs Product List
|Product Name||CAS Number|
|Stenabolic SR 9009||1379686-30-2|
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